1,2-Hexanediol
✓ EU AllowedIdentification
CAS Number 6920-22-5
EINECS / EC 230-029-6
CosIng Ref 54170
Chemical Name hexane-1,2-diol
IUPAC Name —
Formula C6H14O2
Mol. Weight 118.17 g/mol
InChIKey FHKSXSQHXQEMOK-UHFFFAOYSA-N
Function & Classification
Primary Function Solvent
Secondary Functions Humectant, Skin Conditioning
Origin Natural
Category Solvents
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 500 mg/kg bw/day (oral, rat) CIR 2019 / ECHA
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
LD₅₀ Oral 2070 mg/kg (rat)
LD₅₀ Dermal >2000 mg/kg (rabbit)
Skin Irritation (Draize) 0.5 / 4.0
Eye Irritation (Draize) 1.0 / 4.0
Formulation Guidelines
pH Stability 5 – 7.5
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