Polysorbate 20
✓ EU AllowedIdentification
CAS Number 9005-64-5
CosIng Ref 79319
Chemical Name 2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl dodecanoate
Formula C26H50O10
Mol. Weight 522.7 g/mol
Function & Classification
Primary Function Emulsifying
Secondary Functions Surfactant, Thickening
Origin Synthetic
Category Emulsifiers
Manufacturer Eigenmann & Veronelli S.p.A.
EU Regulatory Status
Safety Profile
1 / 10
Fungal Acne Trigger May trigger or worsen fungal acne (feeds Malassezia yeast). Avoid if prone to fungal folliculitis.
Comedogenic Rating: 1/5
Low risk — should be fine for most skin types
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne ✕ May Trigger
Toxicology Profile
NOAEL 5000 mg/kg bw/day (oral, rat) CIR Expert Panel 2015. Int J Toxicol. 34(Suppl 1):4S-30S.
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
Dermal Absorption 1%
LD₅₀ Oral >5000 mg/kg (rat)
LD₅₀ Dermal >2000 mg/kg (rabbit)
Skin Irritation (Draize) 0.2 / 4.0
Eye Irritation (Draize) 0.5 / 4.0
Formulation Guidelines
Usage Level 0.1% – 10%
pH Stability 5 – ?
Solubility miscible a 25
Benefits Surfactant; emulsifier; solubilizer
Suppliers & Documents
Eigenmann & Veronelli S.p.A. 🇮🇹 Italy
Documents