Pentylene Glycol
✓ EU AllowedIdentification
CAS Number 5765-44-6
EINECS / EC 227-367-3
CosIng Ref 58983
Chemical Name 1,2-Dihydroxypentane
Formula C4H5NO
Mol. Weight 83.09 g/mol
Function & Classification
Primary Function Humectant
Secondary Functions SOLVENT
Origin Synthetic
Category Humectants
EU Regulatory Status
Safety Profile
2 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 500 mg/kg bw/day (oral, rat) SCCS/1662/21. Opinion on Pentylene Glycol.
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
Dermal Absorption 50%
LD₅₀ Oral 3700 mg/kg (rat)
LD₅₀ Dermal >2000 mg/kg (rabbit)
Skin Irritation (Draize) 0.3 / 4.0
Eye Irritation (Draize) 0.8 / 4.0
Formulation Guidelines
Usage Level 0.5% – 10%
Benefits Humectant; solvent; antimicrobial booster
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