Urea
✓ EU AllowedAlso known as: Urea, ÜRE 46%
Identification
CAS Number 57-13-6
EINECS / EC 200-315-5
CosIng Ref 38838
Chemical Name urea
IUPAC Name —
Formula CH4N2O
Mol. Weight 60.056 g/mol
InChIKey XSQUKJJJFZCRTK-UHFFFAOYSA-N
Function & Classification
Primary Function Humectant
Secondary Functions BUFFERING; HUMECTANT; SKIN CONDITIONING
Origin Synthetic
Category Humectants
Manufacturer Cosmer Kimya
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 8500 mg/kg bw/day (oral, rat) CIR 2019 / WHO
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
LD₅₀ Oral 14300 mg/kg (rat)
LD₅₀ Dermal >2000 mg/kg (rabbit)
Skin Irritation (Draize) 0.5 / 4.0
Eye Irritation (Draize) 1.0 / 4.0
Formulation Guidelines
Benefits Deep hydration; keratolytic; barrier repair
Suppliers & Documents
Cosmer Kimya 🇹🇷 Turkey
Documents