Butylene Glycol
✓ EU AllowedIdentification
CAS Number 107-88-0
EINECS / EC 203-529-7
CosIng Ref 74756
Chemical Name butane-1,3-diol
IUPAC Name —
Formula C4H10O2
Mol. Weight 90.12 g/mol
InChIKey PUPZLCDOIYMWBV-UHFFFAOYSA-N
Function & Classification
Primary Function Humectant
Secondary Functions FRAGRANCE; SKIN CONDITIONING; SOLVENT; VISCOSITY CONTROLLING
Origin Synthetic
Category Humectants
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 3000 mg/kg bw/day (oral, rat) CIR Expert Panel 2013. Int J Toxicol. 32(Suppl 2):36S-58S.
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
Dermal Absorption 40%
LD₅₀ Oral 18610 mg/kg (rat)
Skin Irritation (Draize) 0.0 / 4.0
Eye Irritation (Draize) 0.2 / 4.0
Formulation Guidelines
Usage Level 0.5% – 20%
pH Stability 5 – 7
Benefits Humectant; solvent; penetration enhancer; antimicrobial booster
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