Azelaic Acid
✓ EU AllowedIdentification
CAS Number 123-99-9
EINECS / EC 204-669-1
CosIng Ref 74538
Chemical Name nonanedioic acid
IUPAC Name —
Formula C9H16O4
Mol. Weight 188.22 g/mol
InChIKey BDJRBEYXGGNYIS-UHFFFAOYSA-N
Function & Classification
Primary Function Keratolytic
Secondary Functions Anti-Acne, Exfoliant
Category Skin Actives
Manufacturer Corum
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 500 mg/kg bw/day (oral, rat, 90-day) SCCS/1446/11 / CIR 2015
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
Dermal Absorption 4%
LD₅₀ Oral 4300 mg/kg (rat)
LD₅₀ Dermal >2000 mg/kg (rabbit)
Skin Irritation (Draize) 1.0 / 4.0
Eye Irritation (Draize) 1.5 / 4.0
Formulation Guidelines
Benefits Acne treatment; brightening; anti-inflammatory
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