Allantoin
✓ EU AllowedIdentification
CAS Number 97-59-6
EINECS / EC 202-592-8
CosIng Ref 31411
Chemical Name (2,5-dioxoimidazolidin-4-yl)urea
IUPAC Name —
Formula C4H6N4O3
Mol. Weight 158.12 g/mol
SMILES C1(C(=O)NC(=O)N1)NC(=O)N
InChIKey POJWUDADGALRAB-UHFFFAOYSA-N
Function & Classification
Primary Function soothing Irritancy: 0 Read where this data comes from and how to interpret it. [more] "> Comedogenicity: 0 Read where this data comes from and how to
Secondary Functions Skin Conditioning, Moisturising
Origin Synthetic
Category Skin Actives
Manufacturer Akema Fine Chemicals S.r.l.
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Irritation Potential 0.0/5
Toxicology Profile
NOAEL 1000 mg/kg bw/day (oral, rat) CIR 2010
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
Dermal Absorption 3%
LD₅₀ Oral >5000 mg/kg (rat)
LD₅₀ Dermal >2000 mg/kg (rabbit)
Skin Irritation (Draize) 0.0 / 4.0
Eye Irritation (Draize) 0.2 / 4.0
Formulation Guidelines
Benefits soothing Irritancy: 0 Read where this data comes from and how to interpret it. [more] "> Comedogenicity: 0 Read where this data comes from and how to, Soothing
Suppliers & Documents
Akema Fine Chemicals S.r.l. 🇮🇹 Italy
Documents