Hydroxyacetophenone
✓ EU AllowedIdentification
CAS Number 99-93-4
EINECS / EC 202-802-8
CosIng Ref 90948
Chemical Name 1-(4-hydroxyphenyl)ethanone
IUPAC Name —
Formula C8H8O2
Mol. Weight 136.15 g/mol
SMILES CC(=O)C1=CC=C(C=C1)O
InChIKey TXFPEBPIARQUIG-UHFFFAOYSA-N
Function & Classification
Primary Function Preservative
Secondary Functions Antimicrobial, Antioxidant
Origin Synthetic
EU Regulatory Status
Safety Profile
2 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 600 mg/kg bw/day (oral, rat, 28-day) Chemsafe GmbH safety assessment. EU REACH registration CAS 99-93-4.
Sensitization Non-sensitizer
Dermal Absorption 25%
Formulation Guidelines
Usage Level 0.05% – 1%
Benefits Preservative booster; antimicrobial; antioxidant; paraben-free system component
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