Ascorbyl Glucoside
✓ EU AllowedIdentification
CAS Number 129499-78-1
EINECS / EC 425-980-0
CosIng Ref 54531
Chemical Name (2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2H-furan-5-one
IUPAC Name —
Formula C12H18O11
Mol. Weight 338.26 g/mol
SMILES C(C1C(C(C(C(O1)OC2=C(C(OC2=O)C(CO)O)O)O)O)O)O
InChIKey MLSJBGYKDYSOAE-DCWMUDTNSA-N
Function & Classification
Primary Function Antioxidant
Secondary Functions Skin Conditioning
Origin Synthetic (enzymatic glycosylation)
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 1000 mg/kg bw/day (oral, rat, 90-day) CIR Expert Panel 2005 (Ascorbic Acid derivatives). Int J Toxicol. 24(Suppl 2).
Sensitization Non-sensitizer
Dermal Absorption 10%
Formulation Guidelines
Usage Level 0.5% – 5%
Benefits Brightening; antioxidant; stable Vitamin C derivative; collagen synthesis; melanin inhibition
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