Biotin
✓ EU AllowedIdentification
CAS Number 58-85-5
EINECS / EC 200-399-3
CosIng Ref 32188
Chemical Name 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid
IUPAC Name —
Formula C10H16N2O3S
Mol. Weight 244.31 g/mol
SMILES C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2
InChIKey YBJHBAHKTGYVGT-ZKWXMUAHSA-N
Function & Classification
Primary Function Skin Conditioning
Secondary Functions SKIN CONDITIONING - MISCELLANEOUS
Origin Synthetic
Category Vitamins & Antioxidants
Manufacturer Hangzhou Rebtech
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL >5000 mg/kg bw/day (oral) CIR 2019 / FDA GRAS
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
LD₅₀ Oral >5000 mg/kg (rat)
Skin Irritation (Draize) 0.0 / 4.0
Eye Irritation (Draize) 0.0 / 4.0
Formulation Guidelines
Benefits Vitamin supplement; supports cellular metabolism
Suppliers & Documents
Hangzhou Rebtech 🇨🇳 China
Documents