Mandelic Acid
⚠ EU RestrictedIdentification
CAS Number 90-64-2
EINECS / EC 202-007-4
CosIng Ref 35152
Chemical Name 2-hydroxy-2-phenylacetic acid
IUPAC Name —
Formula C8H8O3
Mol. Weight 152.15 g/mol
SMILES C1=CC=C(C=C1)C(C(=O)O)O
InChIKey IWYDHOAUDWTVEP-UHFFFAOYSA-N
Function & Classification
Primary Function Exfoliant
Origin Natural
EU Regulatory Status
Max Leave-on 6%
Restrictions Max 6% (leave-on, pH ≥ 3.5). Must include sun protection advice when used in leave-on products.
Conditions of Use Max 6% (leave-on, rinse-off). pH ≥ 3.5.
Mandatory Warning Contains AHA. Apply sunscreen and limit sun exposure while using and for a week afterwards.
SCCS Opinion View SCCS opinion →
Safety Profile
2 / 10
Skin Type Compatibility
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 500 mg/kg bw/day (oral, rat) SCCS/1609/19
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
LD₅₀ Oral 1588 mg/kg (rat)
Skin Irritation (Draize) 1.2 / 4.0
Eye Irritation (Draize) 1.8 / 4.0
Source SCCS Opinion ↗
Formulation Guidelines
Usage level, pH range, solubility and addition phase not yet available.
Usage Level % · Addition Phase · Solubility
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