Methylisothiazolinone
⚠ EU RestrictedIdentification
CAS Number 2682-20-4
EINECS / EC 220-239-6
CosIng Ref 35341
Chemical Name 2-Methyl-2H-isothiazol-3-one
Formula C4H5NOS
Mol. Weight 115.16 g/mol
Function & Classification
Primary Function Preservative
Origin Synthetic
EU Regulatory Status
Max Leave-on 0.0015%
Max Rinse-off 0.0015%
Restrictions 0.0015% (rinse-off only); Prohibited in leave-on products.
Conditions of Use Rinse-off only: max 0.0015% (15 ppm). PROHIBITED in leave-on products.
Mandatory Warning Contains Methylisothiazolinone. For rinse-off products only.
SCCS Opinion View SCCS opinion →
Safety Profile
2 / 10
Known Contact Sensitizer Known to cause allergic contact dermatitis with repeated use or high concentrations.
No toxicology data available yet for this ingredient.
Check SCCS opinions or CIR reports for published safety assessments.
NOAEL · Dermal Absorption % · Sensitization
Formulation Guidelines
Usage level, pH range, solubility and addition phase not yet available.
Usage Level % · Addition Phase · Solubility
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Documents