Imidazolidinyl Urea
⚠ EU RestrictedIdentification
CAS Number 39236-46-9
EINECS / EC 254-372-6
CosIng Ref 34567
Chemical Name N,N'-Methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea]
Formula C11H16N8O8
Mol. Weight 388.29 g/mol
Function & Classification
Primary Function Preservative
Origin Synthetic
EU Regulatory Status
Max Leave-on 0.6%
Max Rinse-off 0.6%
Restrictions 0.6%
Conditions of Use Max 0.6% (formaldehyde-releasing preservative, counted toward total formaldehyde limit of 0.2% leave-on / 0.2% rinse-off).
Mandatory Warning Contains Imidazolidinyl Urea. May release formaldehyde.
SCCS Opinion View SCCS opinion →
Safety Profile
2 / 10
Known Contact Sensitizer Known to cause allergic contact dermatitis with repeated use or high concentrations.
Skin Type Compatibility
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 300 mg/kg bw/day (oral, rat) CIR 2017
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
LD₅₀ Oral >5000 mg/kg (rat)
Skin Irritation (Draize) 0.5 / 4.0
Eye Irritation (Draize) 1.0 / 4.0
Source SCCS Opinion ↗
Formulation Guidelines
Usage level, pH range, solubility and addition phase not yet available.
Usage Level % · Addition Phase · Solubility
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