Cyclohexasiloxane
✓ EU AllowedIdentification
CAS Number 540-97-6
EINECS / EC 208-762-8
CosIng Ref 75406
Chemical Name Dodecamethylcyclohexasiloxane,
Formula C12H36O6Si6
Mol. Weight 444.92 g/mol
Function & Classification
Primary Function Hair Conditioning
Secondary Functions HAIR CONDITIONING; SOLVENT
Origin Synthetic
Category Other
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 1/5
Low risk — should be fine for most skin types
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 50 mg/kg bw/day (inhalation, rat) SCCS/1241/10
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
LD₅₀ Oral >5000 mg/kg (rat)
Skin Irritation (Draize) 0.0 / 4.0
Eye Irritation (Draize) 0.2 / 4.0
Formulation Guidelines
Usage level, pH range, solubility and addition phase not yet available.
Usage Level % · Addition Phase · Solubility
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