Menthol
✓ EU AllowedIdentification
CAS Number 1490-04-6 / 2216-51-5 / 89-78-1 / 15356-70-4
EINECS / EC 216-074-4 / 218-690-9 / 201-939-0 / 239-388-3
CosIng Ref 35228
Chemical Name Cyclohexanol, 5-methyl-2-(1-methylethyl)-
Function & Classification
Primary Function Smoothing
Secondary Functions Cooling Agent, Astringent
Category Skin Actives
EU Regulatory Status
Safety Profile
1 / 10
Skin Type Compatibility
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 40 mg/kg bw/day (oral, rat) CIR 2015 / EFSA
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
LD₅₀ Oral 3300 mg/kg (rat)
LD₅₀ Dermal >5000 mg/kg (rabbit)
Skin Irritation (Draize) 0.8 / 4.0
Eye Irritation (Draize) 1.2 / 4.0
Formulation Guidelines
Benefits Cooling; refreshing; medicinal
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