Tocopheryl Acetate
✓ EU AllowedIdentification
CAS Number 58-95-7
EINECS / EC 200-405-4
CosIng Ref 38627
Chemical Name [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
IUPAC Name —
Formula C31H52O3
Mol. Weight 472.7 g/mol
SMILES CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OC(=O)C)C
InChIKey ZAKOWWREFLAJOT-CEFNRUSXSA-N
Function & Classification
Primary Function Antioxidant
Secondary Functions Skin Protecting, Emollient
Origin Synthetic
Category Vitamins & Antioxidants
Manufacturer BASF SE
EU Regulatory Status
SCCS Opinion View SCCS opinion →
Safety Profile
1 / 10
Comedogenic Rating: 1/5
Low risk — should be fine for most skin types
Skin Type Compatibility
Acne-Prone ✓ Safe
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 1000 mg/kg bw/day (oral, rat, 90-day) CIR Expert Panel 2002. Int J Toxicol. 21(Suppl 3):51-116.
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
Dermal Absorption 2%
LD₅₀ Oral >2000 mg/kg (rat)
Skin Irritation (Draize) 0.0 / 4.0
Eye Irritation (Draize) 0.3 / 4.0
Source SCCS Opinion ↗
Formulation Guidelines
Usage Level 0.1% – 5%
Benefits Antioxidant; skin conditioning; anti-aging; photoprotection support
Suppliers & Documents
BASF SE 🇩🇪 Germany
Documents