Niacinamide
✓ EU AllowedAlso known as: vitamin B3, nicotinamide What-it-does: cell-communicating ingredient , skin brightening , anti-acne , moisturizer/humectant Official CosIng Informatio
Identification
CAS Number 98-92-0
EINECS / EC 202-713-4
CosIng Ref 35499
Chemical Name pyridine-3-carboxamide
IUPAC Name —
Formula C6H6N2O
Mol. Weight 122.12 g/mol
InChIKey DFPAKSUCGFBDDF-UHFFFAOYSA-N
Function & Classification
Primary Function cell-communicating ingredient
Secondary Functions skin brightening, anti-acne, moisturizer, humectant Official CosIng Information All Functions: smoothing CAS #: 98-92
Origin Synthetic
Category Vitamins & Antioxidants
Manufacturer Brother Pharma Co., Ltd.
EU Regulatory Status
Safety Profile
1 / 10
Comedogenic Rating: 0/5
Will not clog pores — safe for acne-prone skin
Skin Type Compatibility
Acne-Prone ✓ Safe
Dry Skin ✓ Beneficial
Fungal Acne Safe ✓ Safe
Toxicology Profile
NOAEL 750 mg/kg bw/day (oral, rat, 13-week) CIR Expert Panel 2005. Int J Toxicol. 24(Suppl 5):1-31.
Sensitization Non-sensitizer
Genotoxicity Non-genotoxic
Phototoxicity Non-phototoxic
Dermal Absorption 30%
LD₅₀ Oral 3500 mg/kg (rat)
LD₅₀ Dermal >2000 mg/kg (rabbit)
Skin Irritation (Draize) 0.0 / 4.0
Eye Irritation (Draize) 0.3 / 4.0
Formulation Guidelines
Usage Level 1% – 10%
pH Stability 6 – 7.5
Solubility amide of nicotinic acid.It is increasingly used in cosmetics, topical creams
Benefits cell-communicating ingredient , skin brightening , anti-acne , moisturizer/humectant Official CosIng Information All Functions: smoothing CAS #: 98-92
Suppliers & Documents
Brother Pharma Co., Ltd. 🇹🇼 Taiwan
Safic Alkan 🇹🇷 Turkey
Documents